Real De Banjul and Bombada United will be playing for a win to clinch the maximum three points.
Brikama United will welcome the newly-promoted side Serrekunda United at the Brikama Box Bar Mini Stadium.
Brikama are mid-table and Serrekunda United are currently rooted at the bottom, and will seek victory against Brikama United to move away from the red zone.
Elsewhere, Interior will play against Gambia Ports Authority at the Serrekunda East Mini Stadium. Both sides are yet to snatch their first win in the league campaign, and will be hoping for a win to grab the vital three points and keep their title ambitions alive.
On Sunday 18 January 2015, Wallidan will face Bakau United at the Serrekunda West Mini Stadium. The Blue boys are currently struggling in the league, and will be expecting to bounce back after losing un two consecutive games, against Hawks 1-0 and Banjul United 2-1.
Banjul United will meet Armed Forces at the Banjul KG5 Mini Stadium, while Gamtel will entertain Hawks at the Serrekunda East Mini Stadium.