Marimoo are among the teams competing for promotion to top flight next season, and will be betting to beat Brufut United to top the summit.
Brufut United are topping the second tier and will be fighting for revenge after losing to Marimoo 3-0 in the first round to revive their lead in the league.
Red Hawks will meet Blue Star at the Banjul KG5 Mini Stadium. The Banjul-based outfit are struggling at the red zone and will be hunting to beat the Wellingara-based outfit to move away from the danger zone.
Blue Star are also among the teams contending for promotion to top flight next season. They will be pushing to smash relegation threatened Red Hawks to fancy their chances.
Tallinding United will welcome Lions of Banjul at the Serrekunda East Mini Stadium. The Tallinding-based outfit are also fighting for promotion to the top flight next season but will face stiff competition from Brufut United, Blue Star, Marimoo, and Interior.
Lions of Banjul are mid-table and will be striving to beat Tallinding United to bounce back after losing to Brufut United 1-0 in the final game of the first round.