The 28-year-old scored his side's opening goal in the 62nd minute after cancelling out Rildo’s opener for Santa Clara.
The Banjul-born player also scored the only goal and guided Boavista to victory during their opening Primeira Liga game against Portimonense last weekend.
Yusupha, who is the son of the late Gambian legendary Biri Biri, now scored in all the Boavista’s fixtures of the new season.
He now helped Boavista to move to 3rd position with 6 points in two matches, leveled with Porto, Benfica and Vitoria Guimaraes.